Stapled Golgi cisternae remain in place as cargo passes through the stack

We have designed a membrane ‘staple’, which consists of membrane-anchored repeats of the trans-aggregating FM domain that face the lumen of the secretory pathway. In the presence of the disaggregating drug these proteins transit the secretory pathway. When the drug is removed these proteins form ele...

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Bibliographic Details
Main Authors: Gregory Lavieu, Hong Zheng, James E Rothman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/00558