Global gene expression profile progression in Gaucher disease mouse models

<p>Abstract</p> <p>Background</p> <p>Gaucher disease is caused by defective glucocerebrosidase activity and the consequent accumulation of glucosylceramide. The pathogenic pathways resulting from lipid laden macrophages (Gaucher cells) in visceral organs and their abnor...

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Bibliographic Details
Main Authors: Zhang Wujuan, Sun Ying, Aronow Bruce, Stringer Keith, Zamzow Matthew, Quinn Brian, Jia Li, Xu You-Hai, Setchell Kenneth DR, Grabowski Gregory A
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/20