Nuclear transport signals control cellular localization and function of androgen receptor cofactor p44/WDR77.

The androgen receptor (AR) cofactor p44/WDR77, which regulates expression of a set of androgen target genes, is required for differentiation of prostate epithelium. Aberrant localization of p44/WDR77 in the cytoplasm is associated with prostate tumorigenesis. Here, we describe studies that used the...

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Bibliographic Details
Main Authors: Zhongping Gu, Liran Zhou, Shen Gao, Zhengxin Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21789256/?tool=EBI