pH and Reduction Dual-Responsive Bi-Drugs Conjugated Dextran Assemblies for Combination Chemotherapy and In Vitro Evaluation

Polymeric prodrugs, synthesized by conjugating chemotherapeutic agents to functional polymers, have been extensively investigated and employed for safer and more efficacious cancer therapy. By rational design, a pH and reduction dual-sensitive dextran-di-drugs conjugate (oDex-g-Pt+DOX) was synthesiz...

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Bibliographic Details
Main Authors: Xiukun Xue, Yanjuan Wu, Xiao Xu, Ben Xu, Zhaowei Chen, Tianduo Li
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/13/9/1515