Combinatorial selection for replicable RNA by Qβ replicase while maintaining encoded gene function.

Combinatorial selection for replicable RNA by Qβ replicase while maintaining encoded gene function.

Construction of a complex artificial self-replication system is challenging in the field of in vitro synthetic biology. Recently, we developed a translation-coupled RNA replication system, wherein an artificial genomic RNA replicates with the Qβ RNA replicase gene encoded on itself. The challenge is...

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Bibliographic Details
Main Authors: Mio Yumura, Natsuko Yamamoto, Katsushi Yokoyama, Hirotada Mori, Tetsuya Yomo, Norikazu Ichihashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5362092?pdf=render

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http://europepmc.org/articles/PMC5362092?pdf=render

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