Angiotensin-(1-7) Prevents Skeletal Muscle Atrophy Induced by Transforming Growth Factor Type Beta (TGF-β) via Mas Receptor Activation

Angiotensin-(1-7) Prevents Skeletal Muscle Atrophy Induced by Transforming Growth Factor Type Beta (TGF-β) via Mas Receptor Activation

Background: Transforming growth factor type beta 1 (TGF-β1) produces skeletal muscle atrophy. Angiotensin-(1-7) (Ang-(1-7)), through the Mas receptor, prevents the skeletal muscle atrophy induced by sepsis, immobilization, or angiotensin II (Ang-II). However, the effect of Ang-(1-7) on muscle wastin...

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Bibliographic Details
Main Authors: Johanna Ábrigo, Felipe Simon, Daniel Cabrera, Claudio Cabello-Verrugio
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Muscle wasting
TGF-β
ng-(1-7)
Mas receptor
MHC
MuRF-1
Online Access:http://www.karger.com/Article/FullText/452522

Internet

http://www.karger.com/Article/FullText/452522

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