Desensitization by Different Strategies of Epidermal Growth Factor Receptor and ErbB4

Desensitization by Different Strategies of Epidermal Growth Factor Receptor and ErbB4

Four transmembrane tyrosine kinases constitute the ErbB protein family: epidermal growth factor receptor (EGFR) or ErbB1, ErbB2, ErbB3, and ErbB4. In general, the structure and mechanism of the activation of these members are similar. However, significant differences in homologous desensitization ar...

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Bibliographic Details
Main Authors: Hideyuki Yamamoto, Sayomi Higa-Nakamine, Nobuhiro Noguchi, Noriko Maeda, Yutaka Kondo, Seikichi Toku, Ichiro Kukita, Kazuhiro Sugahara
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319301781

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http://www.sciencedirect.com/science/article/pii/S1347861319301781

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