Hypoxia-Induced ROS Contribute to Myoblast Pyroptosis during Obstructive Sleep Apnea via the NF-κB/HIF-1α Signaling Pathway

Tissue hypoxia caused by upper airway collapse is a main cause of excessive oxidative stress and systemic inflammation in obstructive sleep apnea (OSA) patients. Increased reactive oxygen species (ROS) and inflammatory responses affect cell survival and ultimately contribute to tissue injury. In the...

Full description

Bibliographic Details
Main Authors: Li-Ming Yu, Wei-Hua Zhang, Xin-Xin Han, Yuan-Yuan Li, Yun Lu, Jie Pan, Jia-Qi Mao, Lu-Ying Zhu, Jia-Jia Deng, Wei Huang, Yue-Hua Liu
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/4596368