Interferon-γ Response of Mycobacterium avium subsp. paratuberculosis Infected Goats to Recombinant and Synthetic Mycobacterial Antigens

Interferon-γ Response of Mycobacterium avium subsp. paratuberculosis Infected Goats to Recombinant and Synthetic Mycobacterial Antigens

Despite its potential for early diagnosis of Mycobacterium avium subsp. paratuberculosis (MAP) infection, the IFN-γ release assay is not used routinely, because of low specificity of the established crude antigen preparation Johnin (PPDj). Limited data are available assessing the potential of MAP-de...

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Bibliographic Details
Main Authors: Heike Köhler, Elisabeth Liebler-Tenorio, Valerie Hughes, Karen Stevenson, Douwe Bakker, Peter Willemsen, Sylvie Bay, Christelle Ganneau, Franck Biet, H. Martin Vordermeier
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Veterinary Science
Subjects:
experimental infection
goat
IFN-gamma response
Mycobacterium avium subsp. hominissuis (MAH)
Mycobacterium avium subsp. paratuberculosis (MAP)
recombinant proteins
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.645251/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.645251/full

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