Effect of a polyphenol-rich dietary pattern on intestinal permeability and gut and blood microbiomics in older subjects: study protocol of the MaPLE randomised controlled trial

Effect of a polyphenol-rich dietary pattern on intestinal permeability and gut and blood microbiomics in older subjects: study protocol of the MaPLE randomised controlled trial

Abstract Background During aging, alterations of the intestinal microbial ecosystem can occur contributing to immunosenescence, inflamm-aging and impairment of intestinal barrier function (increased intestinal permeability; IP). In the context of a diet-microbiota-IP axis in older subjects, food bio...

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Bibliographic Details
Main Authors: Simone Guglielmetti, Stefano Bernardi, Cristian Del Bo’, Antonio Cherubini, Marisa Porrini, Giorgio Gargari, Nicole Hidalgo-Liberona, Raul Gonzalez-Dominguez, Gregorio Peron, Raul Zamora-Ros, Mark S. Winterbone, Benjamin Kirkup, Paul A. Kroon, Cristina Andres-Lacueva, Patrizia Riso
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Geriatrics
Subjects:
Gut barrier function
Leaky gut
Flavonoids
Phenolics
Inflammation
Aging
Online Access:http://link.springer.com/article/10.1186/s12877-020-1472-9

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