Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.

In a process called quorum sensing, bacteria communicate with chemical signal molecules called autoinducers to control collective behaviors. In pathogenic vibrios, including Vibrio cholerae, the accumulation of autoinducers triggers repression of genes responsible for virulence factor production and...

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Bibliographic Details
Main Authors: Hande Boyaci, Tayyab Shah, Amanda Hurley, Bashkim Kokona, Zhijie Li, Christian Ventocilla, Philip D Jeffrey, Martin F Semmelhack, Robert Fairman, Bonnie L Bassler, Frederick M Hughson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.1002464