A novel FZD6 mutation revealed the cause of cleft lip and/or palate in a Chinese family

A novel FZD6 mutation revealed the cause of cleft lip and/or palate in a Chinese family

Cleft lip and/or palate (CL/P) is a most common craniofacial birth defect which has multifactorial etiology. In our study, we aimed to discover the underlying etiological gene variation in a Chinese family diagnosed as non-syndromic CL/P (NSCL/P). The blood sample of the proband and her parents were...

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Bibliographic Details
Main Authors: Jieni Zhang, Huaxiang Zhao, Wenbin Huang, Fengqi Song, Wenjie Zhong, Mengqi Zhang, Yunfan Zhang, Zhibo Zhou, Jiuxiang Lin, Feng Chen
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Genes and Diseases
Subjects:
Cleft lip and/or palate
Frizzled-6
Hereditary pedigree
Variant
Whole-exome sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304219301199

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http://www.sciencedirect.com/science/article/pii/S2352304219301199

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