Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines.

Recent clinical trials investigating receptor tyrosine kinase (RTK) inhibitors showed a limited clinical response in medulloblastoma. The present study investigated the role of micro-environmental growth factors expressed in the brain, such as HGF and EGF, in relation to the effects of hepatocyte gr...

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Bibliographic Details
Main Authors: Walderik W Zomerman, Sabine L A Plasschaert, Sander H Diks, Harm-Jan Lourens, Tiny Meeuwsen-de Boer, Eelco W Hoving, Wilfred F A den Dunnen, Eveline S J M de Bont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4619778?pdf=render