Influence of common non-synonymous Toll-like receptor 4 polymorphisms on bronchopulmonary dysplasia and prematurity in human infants.

Bronchopulmonary dysplasia (BPD) is a common chronic lung disease and major risk factor for severe respiratory syncytial virus (RSV) infection among preterm infants. The Toll-like receptor 4 (TLR4) is involved in oxidative injury responses in the lungs. Two non-synonymous single nucleotide polymorph...

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Bibliographic Details
Main Authors: Pascal M Lavoie, Mihoko Ladd, Aaron F Hirschfeld, Johanna Huusko, Mari Mahlman, David P Speert, Mikko Hallman, Thierry Lacaze-Masmonteil, Stuart E Turvey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3279371?pdf=render