Ex vivo and in vivo chemoprotective activity and potential mechanism of Martynoside against 5-fluorouracil-induced bone marrow cytotoxicity

Ex vivo and in vivo chemoprotective activity and potential mechanism of Martynoside against 5-fluorouracil-induced bone marrow cytotoxicity

Martynoside (MAR) is a bioactive glycoside of Rehmannia glutinosa, a traditional Chinese herb frequently prescribed for treating chemotherapy-induced pancytopenia. Despite its clinical usage in China for thousands of years, the mechanism of MAR’s hematopoietic activity and its impact on chemotherapy...

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Bibliographic Details
Main Authors: Mengying Hong, Dongdong Chen, Zhuping Hong, Kejun Tang, Yuanyuan Yao, Liubo Chen, Tingting Ye, Jing Qian, Yushen Du, Ren Sun
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Martynoside
5-fluorouracil
Bone marrow cytotoxicity
Chemoprotective activity
mRNA-Seq
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221002869

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http://www.sciencedirect.com/science/article/pii/S0753332221002869

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