Synthesis and anti-intracellular Copper overload evaluation of Nanoconjugated D-penicillamine –Dendrimer in Wilson’s model cells

Background and Objective: Wilson’s disease (WD) is caused by mutation to the cooer-transporting gene ATP7B. Chelation therapy is the main protochol of treatment for patients with Wilson’s disease. D-penicillamine is one of the well-known chelator agants which is used in WD treatment but it can not e...

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Bibliographic Details
Main Authors: Fani N, Shafiee Ardestani M, Yaghmaei P, Assadi A, Barzegar Behrouz A
Format: Article
Language:fas
Published: Golestan University of Medical Sciences 2016-03-01
Series:مجله دانشگاه علوم پزشکی گرگان
Subjects:
Online Access:http://goums.ac.ir/journal/browse.php?a_code=A-10-1-876&slc_lang=en&sid=1