Calpain-Calcineurin-Nuclear Factor Signaling and the Development of Atrial Fibrillation in Patients with Valvular Heart Disease and Diabetes

Calpain, calcineurin (CaN), and nuclear factor of activated T cell (NFAT) play a key role in the development of atrial fibrillation. Patients with valvular heart disease (VHD) are prone to develop atrial fibrillation (AF). Thus, our current study was aimed at investigating whether activation of calp...

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Bibliographic Details
Main Authors: Yong Zhao, Guo-ming Cui, Nan-nan Zhou, Cong Li, Qing Zhang, Hui Sun, Bo Han, Cheng-wei Zou, Li-juan Wang, Xiao-dong Li, Jian-chun Wang
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2016/4639654