Functional relationships between recessive inherited genes and genes with de novo variants in autism spectrum disorder

Functional relationships between recessive inherited genes and genes with de novo variants in autism spectrum disorder

Abstract Background Both de novo variants and recessive inherited variants were associated with autism spectrum disorder (ASD). This study aimed to use exome data to prioritize recessive inherited genes (RIGs) with biallelically inherited variants in autosomes or X-linked inherited variants in males...

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Bibliographic Details
Main Authors: Lin Wang, Yi Zhang, Kuokuo Li, Zheng Wang, Xiaomeng Wang, Bin Li, Guihu Zhao, Zhenghuan Fang, Zhengbao Ling, Tengfei Luo, Lu Xia, Yanping Li, Hui Guo, Zhengmao Hu, Jinchen Li, Zhongsheng Sun, Kun Xia
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Molecular Autism
Subjects:
Autism spectrum disorder
Recessive inherited variant
De novo variant
Expression pattern
Functional network
Online Access:http://link.springer.com/article/10.1186/s13229-020-00382-x

Internet

http://link.springer.com/article/10.1186/s13229-020-00382-x

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