Differences in brain pathological changes between rotenone and 6-hydroxydopamine Parkinson’s disease models

Differences in brain pathological changes between rotenone and 6-hydroxydopamine Parkinson’s disease models

Rotenone and 6-hydroxydopamine are two drugs commonly used to generate Parkinson’s disease animal models. They not only achieve degenerative changes of dopaminergic neurons in the substantia nigra, but also satisfy the requirements for iron deposition. However, few studies have compared the characte...

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Bibliographic Details
Main Authors: Lan-Xiang Liu, Dan Du, Zhan-Qiu Wang, Yuan Fang, Tao Zheng, Yan-Chao Dong, Qing-Lei Shi, Min Zhao, Fang Xiao, Juan Du
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; fractional anisotropy; T2FNx01; rotenone; 6-hydroxydopamine; Parkinson′s disease; magnetic resonance imaging; diffusion tensor imaging; dopaminergic neurons; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=7;spage=1276;epage=1280;aulast=Liu

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=7;spage=1276;epage=1280;aulast=Liu

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