Ubiquitous promoter-localization of essential virulence regulators in Francisella tularensis.

Francisella tularensis is a Gram-negative bacterium whose ability to replicate within macrophages and cause disease is strictly dependent upon the coordinate activities of three transcription regulators called MglA, SspA, and PigR. MglA and SspA form a complex that associates with RNA polymerase (RN...

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Bibliographic Details
Main Authors: Kathryn M Ramsey, Melisa L Osborne, Irina O Vvedenskaya, Cathy Su, Bryce E Nickels, Simon L Dove
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4382096?pdf=render