Local administration of HMGB-1 promotes bone regeneration on the critical-sized mandibular defects in rabbits

Local administration of HMGB-1 promotes bone regeneration on the critical-sized mandibular defects in rabbits

Abstract Reconstruction of a critical-sized osseous defect is challenging in maxillofacial surgery. Despite novel treatments and advances in supportive therapies, severe complications including infection, nonunion, and malunion can still occur. Here, we aimed to assess the use of a beta-tricalcium p...

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Bibliographic Details
Main Authors: Ahmed Monir, Taro Mukaibo, Abdel Basit M. Abd El-Aal, Tomotaka Nodai, Takashi Munemasa, Yusuke Kondo, Chihiro Masaki, Mahasen A. El-Shair, Kou Matsuo, Ryuji Hosokawa
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88195-7

Internet

https://doi.org/10.1038/s41598-021-88195-7

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