The Molecular Basis and Biologic Significance of the β-Dystroglycan-Emerin Interaction

The Molecular Basis and Biologic Significance of the β-Dystroglycan-Emerin Interaction

β-dystroglycan (β-DG) assembles with lamins A/C and B1 and emerin at the nuclear envelope (NE) to maintain proper nuclear architecture and function. To provide insight into the nuclear function of β-DG, we characterized the interaction between β-DG and emerin at the molecular level. Emerin is a majo...

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Main Authors: Wendy Lilián Gómez-Monsivais, Feliciano Monterrubio-Ledezma, Jazmin Huerta-Cantillo, Ricardo Mondragon-Gonzalez, Alma Alamillo-Iniesta, Ian García-Aguirre, Paulina Margarita Azuara-Medina, Raúl Arguello-García, Jhon Erick Rivera-Monroy, James M. Holaska, Jesús Mauricio Ernesto Hernández-Méndez, Efraín Garrido, Jonathan Javier Magaña, Steve J. Winder, Andrea Brancaccio, Ivette Martínez-Vieyra, Fernando Navarro-Garcia, Bulmaro Cisneros
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
β-dystroglycan
emerin
nuclear envelope
Emery-Dreifuss muscular dystrophy
surface plasmon resonance assay
proteasome
Online Access:https://www.mdpi.com/1422-0067/21/17/5944

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https://www.mdpi.com/1422-0067/21/17/5944

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