Improved microarray-based decision support with graph encoded interactome data.

In the past, microarray studies have been criticized due to noise and the limited overlap between gene signatures. Prior biological knowledge should therefore be incorporated as side information in models based on gene expression data to improve the accuracy of diagnosis and prognosis in cancer. As...

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Bibliographic Details
Main Authors: Anneleen Daemen, Marco Signoretto, Olivier Gevaert, Johan A K Suykens, Bart De Moor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2856685?pdf=render