Inhibition on Proteasome β1 Subunit Might Contribute to the Anti-Cancer Effects of Fangchinoline in Human Prostate Cancer Cells.

Inhibition on Proteasome β1 Subunit Might Contribute to the Anti-Cancer Effects of Fangchinoline in Human Prostate Cancer Cells.

Fangchinoline is a bisbenzylisoquinoline alkaloid isolated from Radix Stephaniae tetrandrae S. Moore. Fangchinoline and its structure analogue, tetrandrine, exhibited direct binding affinity with recombinant human proteasome β1 subunit and also inhibited its activity in vitro. In cultured prostate P...

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Bibliographic Details
Main Authors: Dong Li, Yu Lu, Peng Sun, Li-Xing Feng, Miao Liu, Li-Hong Hu, Wan-Ying Wu, Bao-Hong Jiang, Min Yang, Xiao-Bo Qu, De-An Guo, Xuan Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4626104?pdf=render

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http://europepmc.org/articles/PMC4626104?pdf=render

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