Chondroitin sulfate proteoglycan CSPG4 as a novel hypoxia-sensitive marker in pancreatic tumors.

CSPG4 marks pericytes, undifferentiated precursors and tumor cells. We assessed whether the shed ectodomain of CSPG4 (sCSPG4) might circulate and reflect potential changes in CSPG4 tissue expression (pCSPG4) due to desmoplastic and malignant aberrations occurring in pancreatic tumors. Serum sCSPG4 w...

Full description

Bibliographic Details
Main Authors: Shereen Keleg, Alexandr Titov, Anette Heller, Thomas Giese, Christine Tjaden, Sufian S Ahmad, Matthias M Gaida, Andrea S Bauer, Jens Werner, Nathalia A Giese
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4059742?pdf=render