Neuroprotective Properties of a Novel Non-Thiazoledinedione Partial PPAR-γ Agonist against MPTP

Activation of the peroxisome proliferator activated receptor-gamma (PPAR)-γ is proposed as a neuroprotective strategy to treat neurodegenerative disorders. In this study, we examined if LSN862 (LSN), a novel non-thiazoledinedione partial PPAR-γ agonist, was neuroprotective in a mouse model of Parkin...

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Bibliographic Details
Main Authors: Christine R. Swanson, Eric Du, Delinda A. Johnson, Jeffrey A. Johnson, Marina E. Emborg
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2013/582809