Phenotypical and Functional Characteristics of Human Regulatory T Cells during Ex Vivo Maturation from CD4+ T Lymphocytes

Phenotypical and Functional Characteristics of Human Regulatory T Cells during Ex Vivo Maturation from CD4+ T Lymphocytes

Regulatory T cells (Tregs) participate in the negative regulation of inflammatory reactions by suppressing effector cells. In a number of autoimmune disorders, the suppressive function and/or the number of Tregs is compromised. The lack of active functioning Tregs can be restored with adoptive trans...

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Bibliographic Details
Main Authors: Varvara G. Blinova, Natalia S. Novachly, Sofya N. Gippius, Abdullah Hilal, Yulia A. Gladilina, Daria D. Eliseeva, Dmitry D. Zhdanov
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Applied Sciences
Subjects:
Tregs expansion
T cell-specific demethylation region
proliferation markers
alternative splicing
telomerase
Online Access:https://www.mdpi.com/2076-3417/11/13/5776

Internet

https://www.mdpi.com/2076-3417/11/13/5776

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