Celastrol Inhibits the Growth of Ovarian Cancer Cells in vitro and in vivo

Celastrol Inhibits the Growth of Ovarian Cancer Cells in vitro and in vivo

Celastrol is a natural triterpene isolated from the Chinese plant Thunder God Vine with potent antitumor activity. However, the effect of celastrol on the growth of ovarian cancer cells in vitro and in vivo is still unclear. In this study, we found that celastrol induced cell growth inhibition, cell...

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Bibliographic Details
Main Authors: Li-Na Xu, Na Zhao, Jin-Yan Chen, Piao-Piao Ye, Xing-Wei Nan, Hai-Hong Zhou, Qi-Wei Jiang, Yang Yang, Jia-Rong Huang, Meng-Ling Yuan, Zi-Hao Xing, Meng-Ning Wei, Yao Li, Zhi Shi, Xiao-Jian Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Oncology
Subjects:
celastrol
reactive oxygen species
N-acetyl-cysteine
apoptosis
ovarian cancer
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00002/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00002/full

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