MRCNN: a deep learning model for regression of genome-wide DNA methylation

Abstract Background Determination of genome-wide DNA methylation is significant for both basic research and drug development. As a key epigenetic modification, this biochemical process can modulate gene expression to influence the cell differentiation which can possibly lead to cancer. Due to the in...

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Bibliographic Details
Main Authors: Qi Tian, Jianxiao Zou, Jianxiong Tang, Yuan Fang, Zhongli Yu, Shicai Fan
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-019-5488-5