Improved final predicted height with the injection of leuprolide in children with earlier puberty: A retrospective cohort study.

The adult height of children with early onset puberty is limited by the premature maturation of hypothalamic-pituitary-gonadal axis. To evaluate the effects of gonadotropin-releasing hormone analog (GnRHa) treatment on the final height (FH) and bone maturation rate (BMR) in girls with early puberty...

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Bibliographic Details
Main Authors: Yi-Chun Lin, Chih-Ying Lin, Siew-Yin Chee, Hung-Rong Yen, Fuu-Jen Tsai, Chiu-Ying Chen, Chung-Hsing Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5626117?pdf=render