The Role of Glial Cells and Synapse Loss in Mouse Models of Alzheimer’s Disease

The Role of Glial Cells and Synapse Loss in Mouse Models of Alzheimer’s Disease

Synapse loss has detrimental effects on cellular communication, leading to network disruptions within the central nervous system (CNS) such as in Alzheimer’s disease (AD). AD is characterized by a progressive decline of memory function, cognition, neuronal and synapse loss. The two main neuropatholo...

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Bibliographic Details
Main Authors: Stephanie Ziegler-Waldkirch, Melanie Meyer-Luehmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Alzheimer’s disease
amyloid plaques
glial cells
synapse loss
microglia
astrocytes
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00473/full

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https://www.frontiersin.org/article/10.3389/fncel.2018.00473/full

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