Characterization of OxyR as a negative transcriptional regulator that represses catalase production in Corynebacterium diphtheriae.

Corynebacterium diphtheriae and Corynebacterium glutamicum each have one gene (cat) encoding catalase. In-frame Δcat mutants of C. diphtheriae and C. glutamicum were hyper-sensitive to growth inhibition and killing by H(2)O(2). In C. diphtheriae C7(β), both catalase activity and cat transcription de...

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Bibliographic Details
Main Authors: Ju-Sim Kim, Randall K Holmes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3306370?pdf=render