The retinoic acid receptor beta (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse.

In neurodegenerative conditions such as Alzheimer's and prion disease it has been shown that host genetic background can have a significant effect on susceptibility. Indeed, human genome-wide association studies (GWAS) have implicated several candidate genes. Understanding such genetic suscepti...

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Bibliographic Details
Main Authors: Julia Grizenkova, Shaheen Akhtar, John Collinge, Sarah E Lloyd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2997791?pdf=render