4-(Phenylsulfanyl)butan-2-One Suppresses Melanin Synthesis and Melanosome Maturation In Vitro and In Vivo

4-(Phenylsulfanyl)butan-2-One Suppresses Melanin Synthesis and Melanosome Maturation In Vitro and In Vivo

In this study, we screened compounds with skin whitening properties and favorable safety profiles from a series of marine related natural products, which were isolated from Formosan soft coral Cladiella australis. Our results indicated that 4-(phenylsulfanyl)butan-2-one could successfully inhibit p...

Full description

Bibliographic Details
Main Authors: Shing-Yi Sean Wu, Hui-Min David Wang, Yi-Shan Wen, Wangta Liu, Pin-Hui Li, Chien-Chih Chiu, Pei-Chin Chen, Chiung-Yao Huang, Jyh-Horng Sheu, Zhi-Hong Wen
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:International Journal of Molecular Sciences
Subjects:
4-(phenylsulfanyl)butan-2-one
melanogenesis
tyrosinase
melanosome maturation
zebrafish
Online Access:http://www.mdpi.com/1422-0067/16/9/20240

Internet

http://www.mdpi.com/1422-0067/16/9/20240

Similar Items