Establishment of an induced pluripotent stem cell line (CSUi003-A) from fibroblasts of a healthy elderly individual

Skin fibroblasts derived from a 71-year-old healthy woman were reprogrammed into induced pluripotent stem cells (iPSCs) by the transduction of retroviruses expressing OCT4, SOX2, KLF4 and c-MYC, respectively. The generated iPSCs maintained a normal karyotype and expressed various pluripotency marker...

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Bibliographic Details
Main Authors: Hongjun Zhao, Lijing Wang, Junjiao Wu, Jie Ren, Qiong Chen, Hui Luo, Xiaoxia Zuo, Yu Tang
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121001720