Neurotropin® Accelerates the Differentiation of Schwann Cells and Remyelination in a Rat Lysophosphatidylcholine-Induced Demyelination Model

Neurotropin® Accelerates the Differentiation of Schwann Cells and Remyelination in a Rat Lysophosphatidylcholine-Induced Demyelination Model

Neurotropin® (NTP), a non-protein extract of inflamed rabbit skin inoculated with vaccinia virus, is clinically used for the treatment of neuropathic pain in Japan and China, although its effect on peripheral nerve regeneration remains to be elucidated. The purpose of this study was to investigate t...

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Bibliographic Details
Main Authors: Hozo Matsuoka, Hiroyuki Tanaka, Junichi Sayanagi, Toru Iwahashi, Koji Suzuki, Shunsuke Nishimoto, Kiyoshi Okada, Tsuyoshi Murase, Hideki Yoshikawa
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
Neurotropin®
Schwann cells
differentiation
AKT
extracellular signal-regulated kinase1/2
remyelination
peripheral nerve
regeneration
Online Access:http://www.mdpi.com/1422-0067/19/2/516

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http://www.mdpi.com/1422-0067/19/2/516

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