Protein meta-functional signatures from combining sequence, structure, evolution, and amino acid property information.
Protein function is mediated by different amino acid residues, both their positions and types, in a protein sequence. Some amino acids are responsible for the stability or overall shape of the protein, playing an indirect role in protein function. Others play a functionally important role as part of...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-09-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2526173?pdf=render |