Detecting and Quantifying Biomolecular Interactions of a Dendritic Polyglycerol Sulfate Nanoparticle Using Fluorescence Lifetime Measurements

Detecting and Quantifying Biomolecular Interactions of a Dendritic Polyglycerol Sulfate Nanoparticle Using Fluorescence Lifetime Measurements

Interactions of nanoparticles with biomaterials determine the biological activity that is key for the physiological response. Dendritic polyglycerol sulfates (dPGS) were found recently to act as an inhibitor of inflammation by blocking selectins. Systemic application of dPGS would present this nanop...

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Bibliographic Details
Main Authors: Alexander Boreham, Jens Pikkemaat, Pierre Volz, Robert Brodwolf, Christian Kuehne, Kai Licha, Rainer Haag, Jens Dernedde, Ulrike Alexiev
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
nanomedicine
dendritic polymers
protein corona
fluorescence lifetime
Online Access:http://www.mdpi.com/1420-3049/21/1/22

Internet

http://www.mdpi.com/1420-3049/21/1/22

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