The Possible Mechanism of Advanced Glycation End Products (AGEs) for Alzheimer's Disease.

The Possible Mechanism of Advanced Glycation End Products (AGEs) for Alzheimer's Disease.

Amyloid precursor protein (APP) has been modified by β and γ-secretase that cause amyloid deposits (plaques) in neuronal cells. Glyceraldhyde-derived AGEs has been identified as a major source of neurotoxicity in Alzheimer's disease (AD). In a previous study, we demonstrated that glyceraldehyde...

Full description

Bibliographic Details
Main Authors: Shun-Yao Ko, Hshin-An Ko, Kuo-Hsiung Chu, Tzong-Ming Shieh, Tzong-Cherng Chi, Hong-I Chen, Weng-Cheng Chang, Shu-Shing Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4654523?pdf=render

Internet

http://europepmc.org/articles/PMC4654523?pdf=render

Similar Items