Value of plasma SN-38 levels and DPD activity in irinotecan-based individualized chemotherapy for advanced colorectal cancer with heterozygous type UGT1A1*6 or UGT1A1*28

Value of plasma SN-38 levels and DPD activity in irinotecan-based individualized chemotherapy for advanced colorectal cancer with heterozygous type UGT1A1*6 or UGT1A1*28

Chuan Tian,1,2,* Haifeng Ying,3,* Rongyuan Zhuang,4 Xiaowei Zhang,5 Hongmin Lu,6 Hui Wang,7 Shuowen Wang,8 Qi Li,1 Chungang Wang,9 Xun Cai1 1Department of Oncology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, People’s Republic of China; 2Dep...

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Bibliographic Details
Main Authors: Tian C, Ying HF, Zhuang RY, Zhang XW, Lu HM, Wang H, Wang SW, Li Q, Wang CG, Cai X
Format: Article
Language:English
Published: Dove Medical Press 2018-11-01
Series:Cancer Management and Research
Subjects:
Irinotecan
pharmacokinetics
enzyme activity
Uridine diphosphate glucuronosyl transferase 1A1
colorectal cancer
Online Access:https://www.dovepress.com/value-of-plasma-sn-38-levels-and-dpd-activity-in-irinotecan-based-indi-peer-reviewed-article-CMAR

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https://www.dovepress.com/value-of-plasma-sn-38-levels-and-dpd-activity-in-irinotecan-based-indi-peer-reviewed-article-CMAR

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