Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells.

Apoptotic cells in animals are engulfed by phagocytic cells and subsequently degraded inside phagosomes. To study the mechanisms controlling the degradation of apoptotic cells, we developed time-lapse imaging protocols in developing Caenorhabditis elegans embryos and established the temporal order o...

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Bibliographic Details
Main Authors: Xiaomeng Yu, Nan Lu, Zheng Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2267821?pdf=render