Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment

Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment

Paclitaxel is a natural, highly lipophilic anti proliferative drug widely used in medicine. We have studied the release of tritium-labeled paclitaxel (<sup>3</sup>H-PTX) from matrices destined for the coating of vascular stents and produced by the electrospinning method from the solution...

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Bibliographic Details
Main Authors: Konstantin A. Kuznetsov, Alena O. Stepanova, Ren I. Kvon, Timothy E. L. Douglas, Nikita A. Kuznetsov, Vera S. Chernonosova, Ivan A. Zaporozhchenko, Maria V. Kharkova, Irina V. Romanova, Andrey A. Karpenko, Pavel P. Laktionov
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Materials
Subjects:
drug release
electrospinning
paclitaxel
polycaprolactone
3D matrix
Online Access:https://www.mdpi.com/1996-1944/11/11/2176

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https://www.mdpi.com/1996-1944/11/11/2176

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