Splatter: simulation of single-cell RNA sequencing data

Abstract As single-cell RNA sequencing (scRNA-seq) technologies have rapidly developed, so have analysis methods. Many methods have been tested, developed, and validated using simulated datasets. Unfortunately, current simulations are often poorly documented, their similarity to real data is not dem...

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Bibliographic Details
Main Authors: Luke Zappia, Belinda Phipson, Alicia Oshlack
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-017-1305-0