Hope for GWAS: Relevant Risk Genes Uncovered from GWAS Statistical Noise

Hope for GWAS: Relevant Risk Genes Uncovered from GWAS Statistical Noise

Hundreds of genetic variants have been associated to common diseases through genome-wide association studies (GWAS), yet there are limits to current approaches in detecting true small effect risk variants against a background of false positive findings. Here we addressed the missing heritability pr...

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Bibliographic Details
Main Authors: Catarina Correia, Yoan Diekmann, Astrid M. Vicente, José B. Pereira-Leal
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:International Journal of Molecular Sciences
Subjects:
genome-wide association studies (GWAS)
missing heritability
protein-protein interaction networks
functional coherence
Online Access:http://www.mdpi.com/1422-0067/15/10/17601

Internet

http://www.mdpi.com/1422-0067/15/10/17601

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