Genetic variants in epidermal growth factor receptor pathway genes and risk of esophageal squamous cell carcinoma and gastric cancer in a Chinese population.

The epidermal growth factor receptor (EGFR) signaling pathway regulates cell proliferation, differentiation, and survival, and is frequently dysregulated in esophageal and gastric cancers. Few studies have comprehensively examined the association between germline genetic variants in the EGFR pathway...

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Bibliographic Details
Main Authors: Wen-Qing Li, Nan Hu, Zhaoming Wang, Kai Yu, Hua Su, Lemin Wang, Chaoyu Wang, Stephen J Chanock, Laurie Burdett, Ti Ding, You-Lin Qiao, Jin-Hu Fan, Yuan Wang, Yi Xu, Carol Giffen, Xiaoqin Xiong, Gwen Murphy, Margaret A Tucker, Sanford M Dawsey, Neal D Freedman, Christian C Abnet, Alisa M Goldstein, Philip R Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3715462?pdf=render