Contrast Enhancement of the Brain by Folate-Conjugated Gadolinium–Diethylenetriaminepentaacetic Acid–Human Serum Albumin Nanoparticles by Magnetic Resonance Imaging

Different from regular small molecule contrast agents, nanoparticle-based contrast agents have a longer circulation time and can be modified with ligands to confer tissue-specific contrasting properties. We evaluated the tissue distribution of polymeric nanoparticles (NPs) prepared from human serum...

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Main Authors: Huedayi Korkusuz, Karsten Ulbrich, Verena Bihrer, Katerina Welzel, Valery Chernikov, Thomas Knobloch, Sabine Petersen, Frank Huebner, Hanns Ackermann, Svetlana Gelperina, Yuecel Korkusuz, Wolfgang Kromen, Renate Hammerstingl, Jörg Haupenthal, Jens Fiehler, Stefan Zeuzem, Jörg Kreuter, Thomas J. Vogl, Albrecht Piiper
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2012-07-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2011.00047