Effect of ligustrazine nanoparticles on Th1/Th2 balance by TLR4/MyD88/NF-κB pathway in rats with postoperative peritoneal adhesion

Abstract Background Postoperative peritoneal adhesion (PPA) is regarded as fibrous bands connecting both injured abdominal wall and organs or adjacent tissues. It is associated with T helper (Th)1 and Th2 differentiation. However, the critical role of the immunopathogenesis of adhesion formation was...

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Bibliographic Details
Main Authors: Lili Yang, Ziyu Lian, Bin Zhang, Zhengjun Li, Li Zeng, Wenlin Li, Yaoyao Bian
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Surgery
Subjects:
Online Access:https://doi.org/10.1186/s12893-021-01201-7