Hepatic trans-Golgi action coordinated by the GTPase ARFRP1 is crucial for lipoprotein lipidation and assembly

The liver is a major organ in whole body lipid metabolism and malfunctioning can lead to various diseases including dyslipidemia, fatty liver disease, and type 2 diabetes. Triglycerides and cholesteryl esters are packed in the liver as very low density lipoproteins (VLDLs). Generation of these lipop...

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Bibliographic Details
Main Authors: Deike Hesse, Katrin Radloff, Alexander Jaschke, Merit Lagerpusch, Bomee Chung, Anne Tailleux, Bart Staels, Annette Schürmann
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520317405