14-3-3 Proteins regulate exonuclease 1-dependent processing of stalled replication forks.
Replication fork integrity, which is essential for the maintenance of genome stability, is monitored by checkpoint-mediated phosphorylation events. 14-3-3 proteins are able to bind phosphorylated proteins and were shown to play an undefined role under DNA replication stress. Exonuclease 1 (Exo1) pro...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-04-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3077382?pdf=render |