Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis.

Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis.

Using A/J mice, which are susceptible to Staphylococcus aureus, we sought to identify genetic determinants of susceptibility to S. aureus, and evaluate their function with regard to S. aureus infection. One QTL region on chromosome 11 containing 422 genes was found to be significantly associated wit...

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Bibliographic Details
Main Authors: Qin Yan, Batu K Sharma-Kuinkel, Hitesh Deshmukh, Ephraim L Tsalik, Derek D Cyr, Joseph Lucas, Christopher W Woods, William K Scott, Gregory D Sempowski, Joshua T Thaden, Thomas H Rude, Sun Hee Ahn, Vance G Fowler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4047107?pdf=render

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http://europepmc.org/articles/PMC4047107?pdf=render

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